YU, Guangjun

Adjunct Professor

Research Field
Medical Big Data, Internet Medicine and Smart Hospital, High-risk Children Management, the Integration of ADHD Medical Education

Professor Guangjun YU, Doctor, Researcher, PhD supervisor; Associate Dean of the School of Medicine of the Chinese University of Hong Kong, Shenzhen; President of National Health Data Institute, Shenzhen; President of Shenzhen Longgang District People's Hospital (the second affiliated to School of Medicine of the Chinese University of Hong Kong, Shenzhen); Head of Medical Information Institute of China Hospital Development Institute, Shanghai Jiao Tong University; Vice President of Pediatric Branch of Shanghai Medical Doctor Association; Vice president of Shanghai Women and Children Research Association; Chairman of Shanghai Medical Association Internet Medical Branch; Standing Committee of Pediatric Branch,and Deputy Chairman of the children health care Special Committee of Chinese Medical Doctor Association; Vice Chairman of Big Data Quality Committee of China Health Information Society; Vice Chairman of Internet Medical Committee of China Medical Information Society. Top 10 of The 4th Session Shanghai Youth Medical Manager.

Academic Publications
  1. Wu D, Cui W, Wang X, Huo Y, Yu G, Chen J. Improvement in outpatient services using the WeChat calling system in the Shanghai Children's Hospital. Pak J Med Sci. 2021 Jul-Aug; 37(4):993-1000
  2. Zhao T, Genchev GZ, Wu S, Yu G, Lu H, Feng J. Pitt-Hopkins syndrome: phenotypic and genotypic description of four unrelated patients and structural analysis of corresponding missense mutations. Neurogenetics. 2021 Jul;22(3):161-169
  3. Hu YB, Chen YT, Liu SJ, Jiang F, Wu MQ, Yan CH, Tan JG, Yu GJ, Hu Y, Yin Y, Qu JJ, Li SH, Tong SL. Increasing prevalence and influencing factors of childhood asthma: a cross-sectional study in Shanghai, China. World J Pediatr. 2021 Aug; 17(4):419-428
  4. Cai X, Genchev GZ, He P, Lu H, Yu G. Demographics, in-hospital analysis, and prevalence of 33 rare diseases with effective treatment in Shanghai. Orphanet J Rare Dis. 2021 Jun 8;16(1):262
  5. Song X, Feng J, Lan X, Tang X, Xu W, Shen J, Yu G, Jia J, Zhang H, Lu Q, Wu S. Generation and characterization of an iPSC line (SHCMDLi001-A) from a 12-year-old Chinese Han patient with TRAF7 syndrome and of an iPSC line (SHCMDLi002-A) from a control individual. Stem Cell Res. 2021 May;53:102377
  6. Hu Y, Jiang F, Tan J, Liu S, Li S, Wu M, Yan C, Yu G, Hu Y, Yin Y, Tong S. Environmental Exposure and Childhood Atopic Dermatitis in Shanghai: A Season-Stratified Time-Series Analysis. Dermatology. 2021 Jun 3:1-8
  7. Ji M, Genchev GZ, Huang H, Xu T, Lu H, Yu G. Evaluation Framework for Successful Artificial Intelligence-Enabled Clinical Decision Support Systems: Mixed Methods Study. J Med Internet Res. 2021 Jun 2;23(6):e25929 
  8. Wu D, Zhu J, Wang X, Shi H, Huo Y, Liu M, Sun F, Lan H, Guo C, Liu H, Li T, Jiang L, Hu X, Li T, Xu J, Yao G, Zhu G, Yu G, Chen J. Rapid BMI Increases and Persistent Obesity in Small-for-Gestational-Age Infants. Front Pediatr. 2021 May 4;9:625853
  9. Hu Y, Chen Y, Liu S, Jiang F, Wu M, Yan C, Tan J, Yu G, Hu Y, Yin Y, Qu J, Li S, Tong S. Breastfeeding duration modified the effects of neonatal and familial risk factors on childhood asthma and allergy: a population-based study. Respir Res. 2021 Feb 6;22(1):41
  10. Wang Y, Gao X, Zhang X, Xiao F, Hu H, Li X, Dong F, Sun M, Xiao Y, Ge T, Li D, Yu G, Liu Z, Zhang T. Microbial and metabolic features associated with outcome of infliximab therapy in pediatric Crohn's disease. Gut Microbes. 2021 Jan-Dec; 13(1): 1-18
  11. Zheng X, Shen L, Jiang L, Shen X, Xu Y, Yu G, Wang Y. Parent and Teacher Training Increases Medication Adherence for Primary School Children With Attention-Deficit/Hyperactivity Disorder. Front Pediatr. 2020 Nov 9;8:486353 
  12. Lan X, Xu W, Tang X, Ye H, Song X, Lin L, Ren X, Yu G, Zhang H, Wu S. Spectrum of RB1 Germline Mutations and Clinical Features in Unrelated Chinese Patients With Retinoblastoma. Front Genet. 2020 Mar 11;11:142 
  13. Cun D, Zhang K, Yu G. Cost Analysis of Operating a Human Milk Bank in China. J Hum Lact. 2020 May;36(2):264-272 
  14. Feng J, Lan X, Shen J, Song X, Tang X, Xu W, Ren X, Zhang H, Yu G, Wu S. A de novo MAPRE2 variant in a patient with congenital symmetric circumferential skin creases type 2. Mol Genet Genomic Med. 2020 Feb;8(2):e1096
  15. Hu Y, Xu Z, Jiang F, Li S, Liu S, Wu M, Yan C, Tan J, Yu G, Hu Y, Yin Y, Tong S. Relative impact of meteorological factors and air pollutants on childhood allergic diseases in Shanghai, China. Sci Total Environ. 2020 Mar 1;706:135975 
  16. Sun H, Guo Y, Lan X, Jia J, Cai X, Zhang G, Xie J, Liang Q, Li Y, Yu G. PhenoModifier: a genetic modifier database for elucidating the genetic basis of human phenotypic variation. Nucleic Acids Res. 2020 Jan 8;48(D1):D977-D982 
  17. Cai X, Yang H, Genchev GZ, Lu H, Yu G. Analysis of economic burden and its associated factors of twenty-three rare diseases in Shanghai. Orphanet J Rare Dis. 2019 Oct 22;14(1):233 
  18. Ji H, Hu Y, Zhang T, Wang Y, Shen L, Wang S, Chen M, Wei M, Yu G. Allergic Comorbidity of Asthma or Wheezing, Allergic Rhinitis, and Eczema: Result From 333 029 Allergic Children in Shanghai, China. Am J Rhinol Allergy. 2020 Mar;34(2):189-195 
  19. Tang C, Sun H, Xiong Y, Yang J, Vitale C, Ruan L, Ai A, Yu G, Ma J, Bates D. Medication Use for Childhood Pneumonia at a Children's Hospital in Shanghai, China: Analysis of Pattern Mining Algorithms. JMIR Med Inform. 2019 Mar 22;7(1):e12577 
  20. Sun H, Yu G. New insights into the pathogenicity of non-synonymous variants through multi-level analysis. Sci Rep. 2019 Feb 7;9(1):1667
  21. Tian Y, Zhang C, Yu G, Hu X, Pu Z, Ma L. Influencing factors of the neurodevelopment of high-risk infants. Gen Psychiatr. 2018 Dec 18;31(3):e100034
  22. Li X, Gao X, Hu H, Xiao Y, Li D, Yu G, Yu D, Zhang T, Wang Y. Clinical Efficacy and Microbiome Changes Following Fecal Microbiota Transplantation in Children With Recurrent Clostridium Difficile Infection. Front Microbiol. 2018 Nov 2;9:2622 
  23. Shi H, Yang X, Wu D, Wang X, Li T, Liu H, Guo C, Wang J, Hu X, Yu G, Chen J. Insights into infancy weight gain patterns for term small-for-gestational-age babies. Nutr J. 2018 Oct 29;17(1):97 
  24. Li XW, Ni X, Qian SY, Wang Q, Jiang RM, Xu WB, Zhang YC, Yu GJ, Chen Q, Shang YX, Zhao CS, Yu H, Zhang T, Liu G, Deng HL, Gao J, Ran XG, Yang QZ, Xu BL, Huang XY, Wu XD, Bao YX, Chen YP, Chen ZH, Liu QQ, Lu GP, Liu CF, Wang RB, Zhang GL, Gu F, Xu HM, Li Y, Yang T. Chinese guidelines for the diagnosis and treatment of hand, foot and mouth disease (2018 edition). World J Pediatr. 2018 Oct;14(5):437-447 
  25. Wang X, Zhu J, Guo C, Shi H, Wu D, Sun F, Shen L, Ge P, Wang J, Hu X, Chen J, Yu G. Growth of infants and young children born small for gestational age: growth restriction accompanied by overweight. J Int Med Res. 2018 Sep;46(9):3765-3777  
  26. Wang X, Zhu J, Guo C, Shi H, Wu D, Sun F, Shen L, Ge P, Wang J, Hu X, Chen J, Yu G. Growth of infants and young children born small for gestational age: growth restriction accompanied by overweight. J Int Med Res. 2018 Sep;46(9):3765-3777
  27. Wang Y, Gao X, Ghozlane A, Hu H, Li X, Xiao Y, Li D, Yu G, Zhang T. Characteristics of Faecal Microbiota in Paediatric Crohn's Disease and Their Dynamic Changes During Infliximab Therapy. J Crohns Colitis. 2018 Feb 28;12(3):337-346
  28. Yu R, Wang Y, Xiao Y, Mo L, Liu A, Li D, Ge T, Yu G, Zhang T. Prevalence of malnutrition and risk of undernutrition in hospitalised children with liver disease. J Nutr Sci. 2017 Oct 30;6:e55 
  29. Ning Q, Li Y, Wang Z, Zhou S, Sun H, Yu G. The Evolution and Expression Pattern of Human Overlapping lncRNA and Protein-coding Gene Pairs. Sci Rep. 2017 Mar 27;7:42775 
  30. Wang J, Gu J, Wang Y, Lin K, Liu S, Lu H, Zhang T, Yu G. 16S rDNA Gene Sequencing Analysis in Functional Dyspepsia Treated With Fecal Microbiota Transplantation. J Pediatr Gastroenterol Nutr. 2017 Mar;64(3):e80-e82 
  31. Wang Y, Li X, Ge T, Xiao Y, Liao Y, Cui Y, Zhang Y, Ho W, Yu G, Zhang T. Probiotics for prevention and treatment of respiratory tract infections in children: A systematic review and meta-analysis of randomized controlled trials. Medicine (Baltimore). 2016 Aug;95(31):e4509 
  32. Gu J, Wang Y, Liu S, Zhang T, Yu G, Lu H. Gut microbiota community adaption during young children fecal microbiota transplantation by 16s rDNA sequencing. Neurocomputing. 2016;06(SI): 66-72 
  33. Carson MB, Gu J, Yu G, Lu H. Identification of cancer-related genes and motifs in the human gene regulatory network. IET Syst Biol. 2015 Aug;9(4):128-34 
  34. Gao Z, Gu Y, Lv Z, Yu G, Zhou J. Practical electronic information system and printed recording promote management accuracy in an early-stage small-scale non-automatic biobank. Biopreserv Biobank. 2015 Feb;13(1):61-6 
  35. Cui W, Zheng P, Yang J, Zhao R, Gao J, Yu G. Integrating clinical and biological information in a shanghai biobank: an introduction to the sample repository and information sharing platform project. Biopreserv Biobank. 2015 Feb;13(1):37-42 
  36. Cao J, Li M, Wang Y, Yu G, Yan C. Environmental lead exposure among preschool children in Shanghai, China: blood lead levels and risk factors. PLoS One. 2014 Dec 1;9(12):e113297 
  37. Zhu Q, Yu G, Yu H, Lu Q, Gu X, Dong Z, Zhang X. A randomized control trial on interruption of HBV transmission in uterus. Chin Med J (Engl). 2003 May;116(5):685-7